Journal Papers
Publications List
2024
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Van Khanh Nguyen, Nhien Nguyen, Zhe-Cheng Li, Chao-Min Cheng, Jui-To Wang, Yu-Wei Chiang, Hsiang-Lin Song, Shih-Kai Lo, Cam Hoa Mac, Yen Chang, Wei-Tso Chia*, and Hsing-Wen Sung* “Inflammation-Activated Endogenous Macrophage-Mediated Prodrug Delivery System Overcoming Biological Barriers for Enhanced Oral Meningitis Therapy” Advanced Functional Materials,2024. (Accepted)
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Cam-Hoa Mac, Hsien-Meng Tai, Sheng-Min Huang, Hsu-Hsia Peng, Amit Kumar Sharma, Giang Le Thi Nguyen, Pei-Ju Chang, Jui-To Wang, Yen Chang, Yu-Jung Lin, Hsing-Wen Sung*, ”Orally Ingested Self-Powered Stimulators for Targeted Gut–Brain Axis Electrostimulation to Treat Obesity and Metabolic Disorders”, Advanced Materials, 202310351, 2024. (SCI IF 29.4)
2023
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Putry Yosefa Siboro+, Amit Kumar Sharma+, Pei-Jhun Lai, Jayachandran Jayakumar, Fwu-Long Mi, Hsin-Lung Chen, Yen Chang*,Hsing-Wen Sung*, "Harnessing HfO2 Nanoparticles for Wearable Tumor Monitoring and Sonodynamic Therapy in Advancing Cancer Care" ACS Nano, 2485–2499,2023. (SCI IF 17.1)
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Cam-Hoa Mac, Hsien-Meng Tai, Sheng-Min Huang, Hsu-Hsia Peng, Amit Kumar Sharma, Giang Le Thi Nguyen, Pei-Ju Chang, Jui-To Wang, Yen Chang, Yu-Jung Lin, Hsing-Wen Sung*, ”Orally Ingested Self-Powered Stimulators for Targeted Gut–Brain Axis Electrostimulation to Treat Obesity and Metabolic Disorders”, Advanced Materials, 2023. Revision under Review (SCI IF 29.4)
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Cheng-Yu Wu+, Cam-Hoa Mac+, Tung-Han Yang+, Khanh Nguyen, Shih-Kai Lo, Yen Chang, Po-Liang Lai, Hsing-Wen Sung*, Yu-Jung Lin*,” Nanoscale Photocatalytic Hydrogen Production System Mitigates Inflammation by Harnessing Glycolysis Waste”, Chemical Engineering Journal, Volume 476,146614, 2023. (SCI IF 15.1)
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Yu-Jung Lin, Po-Kai Luo, Huei-Rou Su, Hung-Yun Lu, Wan-An Chang, Min-Chun Chiang, Hsin-Lung Chen, Kai Chen, Hao-Ji Wei*, Kun-Ju Lin*, Sung, H. W.*, ”A Low-Energy Emulsification Platform Based on a Diet Coke–Mentos Reaction-Derived Bubbly Flow for Formulating Various Emulsions as Drug Carriers”, Biomaterials,122264, 2023 (SCI IF 14.0)
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Kuan-Hung Chen, Tun-Yu Huang, Nhien Nguyen, Yu-Tzu Yu, Yu-Jung Lin, Hsiang-Lin Song, Jui-To Wang, Hsin-Lung Chen, Sung, H. W.* “Macrophage-Hitchhiked Orally Administered β-Glucans-Functionalized Nanoparticles as “Precision-Guided Stealth Missiles” for Targeted Pancreatic Cancer Therapy” Advanced Materials, 2304735. (2023 June) (SCI IF 29.4)
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Chih-Wei Chou, Wei-Tso Chia, Cam-Hoa Mac, Cheng-Yu Wu, Chun-Chieh Chen, Hsiang-Lin Song, Yi-Hsuan Lin, Yu-Jung Lin*, and Sung, H. W.*, “Selective Accumulation of Ionic Nanocrystal H2 Storage System as an In Situ H2/Boric Acid Nanogenerator Fights against Ethanol-Induced Gastric Ulcers“ ,Chemical Engineering J, Volume 463, 142373. (2023 May) (SCI IF 15.1)
2022
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Zhang, Y. C., Wang, M. Y., Zhang, C. Y., Fan, Y. F., Wu, J., Li, S. H., ... Sung, H. W*& Li, R. K. (2022 Nov.). Epicardial delivery of a conductive membrane synchronizes conduction to reduce atrial fibrillation. Journal of Controlled Release, 351, 847-859.(11.467)
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Siboro, P. Y., Nguyen, V. K. T., Miao, Y. B., Sharma, A. K., Mi, F. L., Chen, H. L., ... & Sung, H. W* (2022 Aug). Ultrasound-Activated, Tumor-Specific In Situ Synthesis of a Chemotherapeutic Agent Using ZIF-8 Nanoreactors for Precision Cancer Therapy. ACS Nano, 16(8), 12403-12414. (IF 18.072)
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Mac, C. H., Chan, H. Y., Lin, Y. H., Sharma, A. K., Song, H. L., Chan, Y. S., Lin,K.J., Lin,Y.J., Sung, H. W* (2022 May.) “Engineering a biomimetic bone scaffold that can regulate redox homeostasis and promote osteogenesis to repair large bone defects” Biomaterials, 286, 121574. (IF 15.304)
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Nguyen, N., Lin, Z. H., Barman, S. R., Korupalli, C., Cheng, J. Y., Song, N. X., Chang,Y., Mi,F.-L., Song,H.-L., Sung, H. W*., Lin,Y. J*. (2022 May.)“Engineering an Integrated Electroactive Dressing to Accelerate Wound Healing and Monitor Noninvasively Progress of Healing. “Nano Energy, 107393. (IF: 17.881)
2021
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Miao, Y. B., Lin, Y. J., Chen, K. H., Luo, P. K., Chuang, S. H., Yu, Y. T., Tai, H. M., Chen, C. T., Lin, K. J., Sung, H. W.*, “Engineering Nano- and Microparticles as Oral Delivery Vehicles to Promote Intestinal Lymphatic Drug Transport” Advanced Materials, 2104139, 2021. (SCI 30.85)
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Korupalli, C., Li, H., Nguyen, N., Mi, F. L., Chang, Y., Lin, Y. J.*, Sung, H. W.*, “Conductive Materials for Healing Wounds: Their Incorporation in Electroactive Wound Dressings, Characterization, and Perspectives” Advanced Healthcare Materials, 10(6), 2001384, 2021. (SCI 9.933)
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Miao, Y. B., Chen, K. H., Chen, C. T., Mi, F. L., Lin, Y. J., Chang, Y., Chiang, C.S., Wang, J.T., Lin,K.J., Sung, H. W.* ,“ A noninvasive gut-to-brain oral drug delivery system for Treating Brain Tumors” Advanced Materials, 2100701, 2021(July ). (SCI 30.849)
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Chen, P.-M., Pan, W.-Y.,Luo, P.-K.,Phung, H.-N., Liu, Y.-M., Chiang, M.-C., Chang, W.-A., Tien, T.-L., Huang, C.-Y., Wu, W.-W., Chia, W.-T.*, Sung, H.W*,“Pollen-Mimetic Metal–Organic Frameworks with Tunable Spike-Like Nanostructures That Promote Cell Interactions to Improve Antigen-Specific Humoral Immunity” ACS Nano, vol.15, pp.5775-7836, 2021. (SCI 15.881)
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Hsieh,M.H., Wei,H.J., Chen,K.H., Wang,H.C., Yu,C.H., Lu,T.H., Chang,Y.*, Sung, H.W*,“A fast and facile platform for fabricating phase-change materials-based drug carriers powered by chemical Marangoni effect” Biomaterials, vol.271, pp. 120748, 2021. (SCI 12.497)
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An, Z., Wu, J., Li, S.H., Chen, S., Lu, F.L., Xu, Z.Y., Sung, H.W, Li, R.K.,“Injectable Conductive Hydrogel Can Reduce Pacing Threshold and Enhance Efficacy of Cardiac Pacemaker” Theranostics, vol.11(8), pp3948-3960, 2021. (SCI 11.556)
2020
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Korupalli, C., Li, H., Nguyen, N., Mi, F. L., Chang,Y., Lin,Y.J.*, Sung, H.W*,“Conductive Materials for Healing Wounds: Their Incorporation in Electroactive Wound Dressings, Characterization, and Perspectives” Advanced Healthcare Materials, pp2001384, 2020. (SCI 8.78)
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Chen, P. M., Pan, W. Y., Miao, Y. B., Liu, Y. M., Luo, P. K., Phung, H. N., Wu, W.W., Ting, Y.-H., Yeh, C.-Y., Chiang, M.-C., Chia,W.-T*., Sung, H.W*,“Bioinspired engineering of a bacterium-like metal-organic framework for cancer immunotherapy” Advanced Functional Materials, pp 2003764, 2020. (SCI 18.808)
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He, S., Wu, J., Li, S.H., Wang, L., Sun, Y., Xie, J.; Ramnath, D., Weisel, Richard D., Yau, Terrence M., Sung, H.W; Li, R.K., “The conductive function of biopolymer corrects myocardial scar conduction blockage and resynchronizes contraction to prevent heart failure,” Biomaterials, vol.3, pp. 120285, 2020. (SCI 11.59)
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Chen, K. H., Miao, Y. B., Shang, C. Y., Huang, T. Y., Yu, Y. T., Yeh, C. N., Song, H. L., Chen,C.T., Mi, F. L. , Lin, K. J., Sung, H.W*. ,“A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats,” Biomaterials, vol.255, pp. 120157, 2020. (SCI 11.59)
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Lin, Y.J., Chen, C.C., Dang N., Su, H.R., Lin, K.J., Chen, H.L., Hu, Y.J., Lai, P.L., Sung, H.W*. ,“Biomimetic Engineering of a Scavenger-Free Nitric Oxide-Generating/Delivering System to Enhance Radiation Therapy,” Small, vol 16, pp.2070126, 2020. (SCI 13.281)
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Chen, S., Hsieh, M.H., Li, S.H., Wu, J., Weisel, R.D., Chang, Y., Sung, H.W.*, Li, R.K.* , “A Conductive Cell-Delivery Construct as a Bioengineered Patch that Can Improve Electrical Propagation and Synchronize Cardiomyocyte Contraction for Heart Repair,” Journal of Controlled Release, vol.320, pp.73-82, 2020. (SCI 8.66)
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Wan, W.L., Tian, B. Lin, Y.J., Korupalli, C., Lu, M.Y., Cui, Q., Wan, D.H., Chang, Y.*, Sung, H.W.*, “Photosynthesis-Inspired H2 Generation Using a Chlorophyll-Loaded Liposomal Nanoplatform to Detect and Scavenge Excess ROS,” Nature Communications, vol.11, pp.534, 2020. (SCI 14.919)
2019
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Zhang, C., Hsieh, M. H., Wu, S. Y., Li, S. H., Wu, J., Liu, S.M., Wei, H.J., Weisel, R.D., Sung, H.W.*, Li, R.K.*, “A self-doping conductive polymer hydrogel that can restore electrical impulse propagation at myocardial infarct to prevent cardiac arrhythmia and preserve ventricular function,” Biomaterials, vol.231, pp. 119672, 2019. (SCI 11.59)
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Cui, Q., Le, T. H., Lin, Y. J., Miao, Y. B., Sung, I. T., Tsai, W. B., Chan, H.Y., Lin, Z.H.*, Sung, H. W.*, “A self-powered battery-driven drug delivery device that can function as a micromotor and galvanically actuate localized payload release,” Nano Energy, vol.66, pp. 104120, 2019. (SCI 16.88)
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Miao, Y.B., Pan, W.Y., Chen, K.H., Wei, H.J., Mi, F.L., Lu, M.Y., Chang, Y.*, Sung, H.W.*, “Engineering a Nanoscale Al‐MOF‐Armored Antigen Carried by a “Trojan Horse”‐Like Platform for Oral Vaccination to Induce Potent and Long‐Lasting Immunity,” Advanced Functional Materials, vol.29, pp. 1904828, 2019. (SCI 18.808)
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Hsieh, M.H., Tsai, H.W., Lin, K.J., Wu, Z.Y., Hu, H.Y., Chang, Y., Wei, H.J.*, Sung, H.W.*, “An in situ slow-releasing H2S donor depot with long-term therapeutic effects for treating ischemic diseases,” Materials Science and Engineering:C, vol.104, pp. 109954, 2019 (SCI 7.06)
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Chen, P.M., Pan, W.Y., Wu, C.Y., Yeh, C.Y., Korupalli, C., Luo, P.K., Chou, C.J., Chia, W.T.*, Sung, H.W.*, “Modulation of tumor microenvironment using a TLR-7/8 agonist-loaded nanoparticle system that exerts low-temperature hyperthermia and immunotherapy for in situ cancer vaccination,” Biomaterials, vol.15, pp. 119629, 2019. (SCI 11.59)
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Korupalli, C., Pan, W.-Y., Yeh, C.-Y., Chen, P.-M., Mi, F.-L., Tsai, H.-W., Chang, Y., Wei, H.-J.*, Sung, H.-W.*, “Single-injecting, bioinspired nanocomposite hydrogel that can recruit host immune cells in situ to elicit potent and long-lasting humoral immune responses,” Biomaterials, vol. 216, pp. 119268, 2019. (SCI 11.59)
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Lin, P.-Y., Chen, K.-H., Miao, Y.-B., Chen, H.-L., Lin, K.-J., Chen, C.-T., Yeh, C.‐N., Chang, Y.*, Sung, H.-W.*, “Phase‐Changeable Nanoemulsions for Oral Delivery of a Therapeutic Peptide: Toward Targeting the Pancreas for Antidiabetic Treatments Using Lymphatic Transport,” Advanced Functional Materials, vol.29, pp. 1809015, 2019. (SCI 18.808)
2018
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Lin, Y.-J., Mi, F.-L., Lin, P.-Y., Miao, Y.-B., Huang, T., Chen, K.-H., Chen, C.-T., Chang, Y.*, Sung, H.-W.*, “Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems,” Advanced Drug Delivery Reviews, vol. 139, pp. 71-82, 2018. (SCI 13.300)
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Lin, W.-C., Pan, W.-Y., Liu, C.-K., Huang, W.-X., Song, H.-L., Chang, K.-S., Li, M.-J.*, Sung, H.-W.* “ In situ self-spray coating system that can uniformly disperse a poorly water-soluble H2S donor on the colorectal surface to treat inflammatory bowel diseases,” Biomaterials, vol. 182, pp. 289-298, 2018. (SCI 11.59)
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Lin, P.-Y., Chiu, Y.-L., Huang, J.-H., Chuang, E.-Y., Mi, F.-L., Lin, K.-J., Juang, J.-H., Sung, H.-W.*, Leong, K. W.*, “Oral Nonviral Gene Delivery for Chronic Protein Replacement Therapy,” Advanced Science. vol.5, 1701079, 2018. (SCI 16.806)
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Wan, W.-L., Lin, Y.-J., Shih, P.-C., Bow, Y.-R., Cui, Q., Chang, Y., Chia, W.-T.*, Sung, H.-W.*,” An In Situ Depot for Continuous Evolution of Gaseous H2 Mediated by a Magnesium Passivation/Activation Cycle for Treating Osteoarthritis,” Angew Chem Int Ed Engl. vol. 57, pp. 9875-9879, 2018. (SCI15.336)
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Chuang, E.-Y.+, Lin, K.-J.+, Huang, T.-Y., Chen, H.-L., Miao, Y.-B., Lin, P.-Y., Chen, C.-T., Juang, J.-H*, Sung, H.-W.*, An Intestinal “Transformers”-Like Nanocarrier System for Enhancing the Oral Bioavailability of Poorly Water-Soluble Drugs, ACS Nano. vol.12, pp. 6389-6397, 2018. (SCI 15.881)
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Lin, Y.-J.+, Chen, C.-C.+, Chi, N.-W., Nguyen, T., Lu, H.-Y., Nguyen, D., Lai, P.-L.*, Sung, H.-W.*, “In situ self-assembling micellar depots that can actively trap and passively release NO with long-lasting activity to reverse osteoporosis,” Advanced Materials. vol.30, 1705605, 2018. (SCI 30.849)
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Cui, Z., Ni, N.-C., Wu, J., Du, G.-Q., He, S., Yau, T.-M., Weisel, R.-D., Sung, H.-W., Li, R.-K.* “Polypyrrole-Chitosan Conductive Biomaterial Synchronizes Cardiomyocytes Contraction and Improves Myocardial Electrical Impulse Propagation,” Theranostics. vol. 8, pp. 2752–2764, 2018. (SCI 11.556)
2017
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Lin, W.-C., Huang, C.-C., Lin, S.-J., Li, M.-J., Chang, Y., Lin, Y.-J., Wan W.-L., Shih, P.-C., Sung, H.-W.*, “In situ depot comprising phase-change materials that can sustainably release a gasotransmitter H2S to treat diabetic wounds,” Biomaterials, vol. 145, pp.1–8, 2017. (SCI 11.59)
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Wan, W.-L., Lin, Y.-J., Chen, H.-L., Huang, C.-C., Shih, P.-C., Bow, Y.-R., Chia, W.-T.*, Sung, H.-W.* "In Situ Nanoreactor for Photosynthesizing H2 Gas to Mitigate Oxidative Stress in Tissue Inflammation," Journal of the American Chemical Society, vol. 139, pp. 12923-12926, 2017. (SCI 15.419)
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Lin, P.-Y., Chuang, E.-Y., Chiu, Y.-H., Chen, H.-L., Lin, K.-J., Juang, J.-H., Chiang, C.-H., Mi, F.-L.*, Sung, H.-W.* “Safety and efficacy of self-assembling bubble carriers stabilized with sodium dodecyl sulfate for oral delivery of therapeutic proteins,” Journal of Controlled Release, vol. 256, pp. 168-175, 2017. (SCI 8.66)
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Lin, Y.-J., Huang, C.-C., Wan W.-L., Chiang, C.-H., Chang, Y., Sung, H.-W.*, “Recent advances in CO2 bubble-generating carrier systems for localized controlled release,” Biomaterials, vol. 133, pp. 154–164, 2017. (SCI 11.59)
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Pelaz, B., Alexiou, C., Puebla, R.A.A., Alves, F., Andrews, A.M., Ashraf, S., …, Sung, H.-W., …, Parak, W.J.*, “Diverse Applications of Nanomedicine,” ACS Nano, vol. 11, pp. 2313–2381, 2017. (SCI 15.881)
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Korupalli, C., Huang, C.-C., Lin, W.-C., Pan, W.-Y., Lin, P.-Y., Wan, W.-L., Li, M.-J., Chang, Y.*, Sung, H.-W.*, “Acidity-triggered charge-convertible nanoparticles that can cause bacterium-specific aggregation in situ to enhance photothermal ablation of focal infection,” Biomaterials, vol. 116, pp. 1–9, 2017. (SCI 11.59)
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Lu, K.-Y., Lin, P.-Y., Chuang, E.-Y., Shih, C.-M., Cheng, T.-M., Lin, T.-Y., Sung, H.-W.*, Mi, F.-L.*, “H2O2-depleting and O2-generating selenium nanoparticles for fluorescence imaging and photodynamic treatment of proinflammatory-activated macrophages,” ACS Applied Materials & Interfaces, vol. 9, pp. 5158–5172, 2017. (SCI 9.229)
2016
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Huang, C.-C., Liao Z.-X., Lu H.-M., Pan, W.-Y., Wan W.-L., Chen C.-C. , Sung, H.-W.*, “Cellular Organelle-Dependent Cytotoxicity of Iron Oxide Na-noparticles and Its Implications for Cancer Diagnosis and Treatment: A Mechanistic Investigation,” Chemistry of Materials, vol. 28, pp. 9017–9025, 2016. (SCI 8.97 )
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Pan, W.-Y., Lin, K.-J., Huang, C.-C., Chiang, W.-L., Lin, Y.-J., Lin, W.-C., Chuang, E.-Y., Chang, Y.*, Sung, H.-W.*, “Localized sequence-specific release of a chemopreventive agent and an anticancer drug in a time-controllable manner to enhance therapeutic efficacy,” Biomaterials, vol. 101, pp. 241–250, 2016. (SCI 11.59)
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Chuang, E.-Y., Lin, C.-C., Chen, K.-J., Wan, D.-H., Lin, K.-J., Ho, Y.-C., Lin, P.-Y., Sung, H.-W.*, “A FRET-guided, NIR-responsive bubble-generating liposomal system for in vivo targeted therapy with spatially and temporally precise controlled release,” Biomaterials, vol. 93, pp. 48–59, 2016. (SCI 11.59)
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Huang, C.-C., Chia, W.-T., Chung, M.-F., Lin, K.-J., Hsiao, C.-W., Jin, C., Lim, W.-H., Chen, C.-C., Sung, H.-W.*, “An Implantable Depot That Can Generate Oxygen in Situ for Overcoming Hypoxia-Induced Resistance to Anticancer Drugs in Chemotherapy,” Journal of the American Chemical Society, vol. 138, pp. 5222–5225, 2016. (SCI 15.419)
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Lin, C.-W., Lu, K.-Y., Wang, S.-Y., Sung, H.-W.*, Mi, F.-L.*, “CD44-specific nanoparticles for redox-triggered reactive oxygen species production and doxorubicin release,” Acta Biomaterialia, vol. 35, pp. 280–2992, 2016. (SCI 6.383)
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Pan, W.-Y., Huang, C.-C., Lin, T.-T., Hu, H.-Y., Lin, W.-C., Li, M.-J.*, Sung, H.-W.*, “Synergistic antibacterial effects of localized heat and oxidative stress caused by hydroxyl radicals mediated by graphene/iron oxide-based nanocomposites,” Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 12, pp. 431–438, 2016. (SCI 6.5)
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Huang, C.-C., Pan, W.-Y., Tseng, M.-T., Lin, K.-J., Yang, Y.-P., Tsai, H.-W., Hwang, S.-M., Chang, Y., Wei, H.-J.*, Sung, H.-W.*, “Enhancement of cell adhesion, retention, and survival of HUVEC/cbMSC aggregates that are transplanted in ischemic tissues by concurrent delivery of an antioxidant for therapeutic angiogenesis,” Biomaterials, vol. 74, pp. 53–63, 2016. (SCI 11.59)